I was getting a "Failed to import the required Python library (setuptools) on [machine name]'s Python /usr/bin/python." Part of the issue is that I have Python 2 and Python 3 running on my Raspberry Pi.  After digging through the web, I found this article on Stack Overflow that fixed the issue for me.

The gist of it was to run this command:

update-alternatives --install /usr/bin/python python /usr/bin/python3 10

This is a cleaner way than to do an alias as this allows the user to still run a sudo command on python